Recombinant Cytokeratin 8 Monoclonal Antibody
Product Specifications
Background
KRT8 (keratin 8) Homo sapiens This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene.
Abbreviation
Cytokeratin 8
UniProt
P05787
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant Human Cytokeratin 8 protein
Target
CYK; KRT; CYK8; KRT8; CARD2; CARD2; CK 8; CK-8; CK8; CYK8; CYKER; Cytokeratin endo A; Cytokeratin-8; DreK8; EndoA; K2C8; K2C8; K8; Keratin 8; Keratin type II cytoskeletal 8; Keratin; type II cytoskeletal 8; Keratin-8; KO; Krt 2.8; KRT8; MGC118110; MGC174782; MGC53564; MGC85764; sb:cb186; Type-II keratin Kb8; CK 8; CK8; CK-8; CYKER; Cytokeratin endo A; Cytokeratin-8; DreK8; EndoA; K2C8; Keratin; Keratin 8; Keratin type II cytoskeletal 8; Keratin-8; Krt 2.8; MGC118110; MGC174782; MGC53564; MGC85764; sb:cb186; type II cytoskeletal 8; Type-II keratin Kb8
Clonality
Monoclonal,Recombinant
Clone
6F6
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Signal Transduction; Cancer
Purification
Protein A
Concentration
0.2 mg/mL
Dilution
IHC 1:200-1:1000; WB 1:1000-1:5000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
54 kDa
Observed Molecular Weight
54 kDa
Isotype
IgG, κ
Available Sizes
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