Recombinant FTO Monoclonal Antibody
Product Specifications
Background
This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes.
Abbreviation
FTO
UniProt
Q9C0B1
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant Human FTO protein
Target
BMIQ; AlkB homolog; KIAA; ALKBH; mKIAA; FTO; ALKBH9; BMIQ14; GDFD; AlkB homolog 9; Alpha-ketoglutarate-dependent dioxygenase FTO; AW743446; Fat mass and obesity-associated protein; FATSO; HOMOLOG OF; mKIAA1752; MOUSE; Protein fatso; KIAA1752
Clonality
Monoclonal,Recombinant
Clone
5F4
Conjugation
Unconjugated
Applications
WB
Field of Research
Neuroscience; Cardiovascular; Metabolism
Purification
Protein A
Concentration
0.2 mg/mL
Dilution
WB 1:1000-1:5000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
58 kDa
Observed Molecular Weight
58 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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