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Recombinant FTO Monoclonal Antibody

Product Specifications

Background

This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes.

Abbreviation

FTO

UniProt

Q9C0B1

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Recombinant Human FTO protein

Target

BMIQ; AlkB homolog; KIAA; ALKBH; mKIAA; FTO; ALKBH9; BMIQ14; GDFD; AlkB homolog 9; Alpha-ketoglutarate-dependent dioxygenase FTO; AW743446; Fat mass and obesity-associated protein; FATSO; HOMOLOG OF; mKIAA1752; MOUSE; Protein fatso; KIAA1752

Clonality

Monoclonal,Recombinant

Clone

5F4

Conjugation

Unconjugated

Applications

WB

Field of Research

Neuroscience; Cardiovascular; Metabolism

Purification

Protein A

Concentration

0.2 mg/mL

Dilution

WB 1:1000-1:5000

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

58 kDa

Observed Molecular Weight

58 kDa

Isotype

IgG, κ

Available Sizes

Curated Selection

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