Recombinant RPA32/RPA2 Monoclonal Antibody

Required for DNA recombination, repair and replication. The activity of RP-A is mediated by single-stranded DNA binding and protein interactions., PTM:Phosphorylated in a cell-cycle-dependent manner (from the S phase until mitosis) . Phosphorylated by ATR upon DNA damage, which promotes its translocation to nuclear foci. Can be phosphorylated in vitro by PRKDC/DNA-PK in the presence of Ku and DNA, and by CDC2., subcellular location:Also present in PML nuclear bodies. Redistributes to discrete nuclear foci upon DNA damage., subunit:Heterotrimer of 70, 32 and 14 kDa chains. The DNA-binding activity may reside exclusively on the 70 kDa subunit. Binds to SERTAD3/RBT1. Interacts with TIPIN.

REPA; RPA; REPA2; RP-A p32; RP-A p34; RPA32; RPA2; RP-Ap32; RP-Ap34; RPA34;32kDa;60S acidic ribosomal protein P1; AA409079; AI325195; AU020965; ik:tdsubc_2g1; M (2) 21C; MGC137236; OTTHUMP00000004008; p32; p34; RCJMB04_6d17 replication protein A2; Replication factor A protein 2; Replication protein A; Replication protein A 32 kDa subunit; Replication protein A 32kDa subunit; Replication protein A 34 kDa subunit; Replication protein A2; Replication Protein A2 (32kDa) ; RFA; RF-A protein 2; RFA2; Rf-A2; RP21C; RPA 2; RPA 32; RpLP1; RpP2; xx:tdsubc_2g1; zgc:109822; RFA2