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Recombinant IRF3 Monoclonal Antibody

Product Specifications

Background

This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Abbreviation

IRF3

UniProt

Q14653

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Recombinant Human IRF3 protein

Target

IRF; IRF3; entrez:3661; IIAE7; IRF-3; IRF-3

Clonality

Monoclonal,Recombinant

Clone

4F6

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Immunology; Epigenetics and Nuclear Signaling

Purification

Protein A

Concentration

0.2 mg/mL

Dilution

IHC 1:200-1:1000; WB 1:500-1:2000

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

47 kDa

Observed Molecular Weight

55 kDa

Isotype

IgG, κ

Available Sizes

Curated Selection

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