Recombinant CD38 Monoclonal Antibody
Product Specifications
Background
The protein encoded by this gene is a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5'-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Crystal structure analysis demonstrates that the functional molecule is a dimer, with the central portion containing the catalytic site. It is used as a prognostic marker for patients with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants.
Abbreviation
CD38
UniProt
P28907
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant Human CD38 protein
Target
CADPr hydrolase; ADP-ribosyl cyclase; cyclic ADP-ribose hydrolase; Acute lymphoblastic leukemia cells antigen CD; ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase; CD38; ADPRC 1; ADPRC1; Acute lymphoblastic leukemia cells antigen CD38; ADP ribosyl cyclase; ADP-ribosyl cyclase 1; ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1; cADPr hydrolase 1; CD38 antigen; CD38 molecule; CD38H; Cyclic ADP ribose hydrolase; EC 3.2.2.5; I-19; NIMR5 antigen; p45; ADP-ribosyl; T10; cyclase;2'-phospho-ADP-ribosyl cyclase;2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase;2'-phospho-cyclic-ADP-ribose transferase; ADP-ribosyl cyclase 1 (ADPRC 1) ; Cyclic ADP-ribose hydrolase 1 (cADPr hydrolase 1) ; cyclic ADP-ribose hydrolase 1; ADP-ribosyl cyclase; ADP ribosyl cyclase; ADPRC1; CD38 antigen; CD38 molecule; CD38H; Cyclic ADP ribose hydrolase; EC 3.2.2.5; I-19; NIMR5 antigen; p45; T10; Acute lymphoblastic leukemia cells antigen CD38; ADP ribosyl cyclase; ADPRC1; CD38 antigen; CD38 molecule; CD38H; Cyclic ADP ribose hydrolase; EC 3.2.2.5; I-19; NIMR5 antigen; p45; T10; ADP ribosyl cyclase 1; ADP ribosyl cyclase/cyclic ADP-ribose hydrolase; CD 38; CD38 antigen (p45) ; Cd38-rs1; Cyclic ADP ribose hydrolase 1; Ecto nicotinamide adenine dinucleotide glycohydrolase; I19 (mouse) ; Lymphocyte differentiation antigen CD38; NAD (+) nucleosidase; NIM-R5 antigen; NIMR5 antigen (mouse) ; OTTHUMP00000158633; OTTHUMP00000217743
Clonality
Monoclonal,Recombinant
Clone
3F10
Conjugation
Unconjugated
Applications
WB
Field of Research
Immunology; Stem Cells; Cancer; Metabolism
Purification
Protein A
Concentration
0.2 mg/mL
Dilution
WB 1:1000-1:5000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Product MSDS
https://789.bio/eb/wqhY0vQw
Calculated Molecular Weight
34 kDa
Observed Molecular Weight
45 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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