Recombinant Histone H2B Monoclonal Antibody
Product Specifications
Background
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4) . The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2B family. Two transcripts that encode the same protein have been identified for this gene, which is found in the large histone gene cluster on chromosome 6p22-p21.3.
Abbreviation
Histone H2B
UniProt
P62807; P58876; Q93079; O60814; Q99880; Q99879; Q99877; Q5QNW6; P57053
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant Human Histone H2B protein
Target
HIST1H2BG; H2B.1A; H2B/a; H2BFA; H2BFL; HIST1H2BC; H2BFH; HIST1H2BE; H2BFG; HIST1H2BF; H2BFK; HIST1H2BI; H2BC4; H2BC6; H2BC7; H2BC8; H2BC10
Clonality
Monoclonal,Recombinant
Clone
9C9
Conjugation
Unconjugated
Applications
WB
Field of Research
Epigenetics and Nuclear Signaling
Purification
Protein A
Concentration
0.2 mg/mL
Dilution
WB 1:1000-1:5000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
14 kDa
Observed Molecular Weight
14 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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