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Recombinant BMP2 Monoclonal Antibody

Product Specifications

Background

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of this gene causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients.

Abbreviation

BMP2

UniProt

P12643

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Recombinant Human BMP2 protein

Target

BDA; BMP; BDA2; BMP2A; BMP2; BDA2A; BMP-2; BMP-2A; Bone morphogenetic protein 2; Bone morphogenetic protein 2A; BMP-2

Clonality

Monoclonal,Recombinant

Clone

9C1

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Signal Transduction; Stem Cells; Cancer; Cardiovascular

Purification

Protein A

Concentration

0.2 mg/mL

Dilution

IHC 1:200-1:1000; WB 1:1000-1:5000

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Product MSDS

https://789.bio/eb/lQWP5VmR

Calculated Molecular Weight

45 kDa,13 kDa

Observed Molecular Weight

30 kDa,13 kDa

Isotype

IgG, κ

Available Sizes

Curated Selection

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