Recombinant BMP2 Monoclonal Antibody
Product Specifications
Background
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of this gene causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients.
Abbreviation
BMP2
UniProt
P12643
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant Human BMP2 protein
Target
BDA; BMP; BDA2; BMP2A; BMP2; BDA2A; BMP-2; BMP-2A; Bone morphogenetic protein 2; Bone morphogenetic protein 2A; BMP-2
Clonality
Monoclonal,Recombinant
Clone
9C1
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Signal Transduction; Stem Cells; Cancer; Cardiovascular
Purification
Protein A
Concentration
0.2 mg/mL
Dilution
IHC 1:200-1:1000; WB 1:1000-1:5000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
45 kDa,13 kDa
Observed Molecular Weight
30 kDa,13 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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