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Recombinant PAK1 Monoclonal Antibody

Product Specifications

Background

This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Abbreviation

PAK1

UniProt

Q13153

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Recombinant Human PAK1 protein

Target

PAK; PAK1; PAKalpha; ADRB2; Alpha PAK; Alpha-PAK; MGC130000; MGC130001; p21 activated kinase 1; p21 protein (Cdc42/Rac) activated kinase 1; p21/Cdc42/Rac1 activated kinase 1 (yeast Ste20 related) ; p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog; p21-activated kinase 1; p65 PAK; p65-PAK; P68-PAK; PAK alpha; PAK-1; Paka; Protein kinase MUK2; Rac/p21-activated kinase; Serine/threonine-protein kinase PAK 1; STE20 homolog yeast; yeast)

Clonality

Monoclonal,Recombinant

Clone

8C11

Conjugation

Unconjugated

Applications

WB

Field of Research

Cell Biology; Signal Transduction; Cancer; Microbiology; Neuroscience

Purification

Protein A

Concentration

0.2 mg/mL

Dilution

WB 1:1000-1:5000

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

61 kDa

Observed Molecular Weight

61 kDa

Isotype

IgG, κ

Available Sizes

Frequently Asked Questions

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