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Recombinant Caldesmon Monoclonal Antibody

Product Specifications

Background

This gene encodes a calmodulin- and actin-binding protein that plays an essential role inThe regulation of smooth muscle and nonmuscle contraction.The conserved domain of this protein possessesThe binding activities to Ca (2+) -calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor ofThe actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca (2+) -dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.

Abbreviation

Caldesmon

UniProt

Q05682

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Recombinant Human Caldesmon protein

Target

NAG; MGC; CALD1; CDM; H-CAD; HCAD; L-CAD; LCAD; NAG22; caldesmon; CALD 1; Caldesmon 1; Caldesmon 1 Isoform 1; Caldesmon 1 Isoform 2; Caldesmon 1 Isoform 3; Caldesmon 1 Isoform 4; Caldesmon 1 Isoform 5; Caldesmon1; H CAD; L CAD; MGC21352; CAD; CAD; CALD 1; CALD1; CALD1; Caldesmon 1; Caldesmon 1 Isoform 1; Caldesmon 1 Isoform 2; Caldesmon 1 Isoform 3; Caldesmon 1 Isoform 4; Caldesmon 1 Isoform 5; Caldesmon; Caldesmon1; CDM; H CAD; HCAD; L CAD; LCAD; MGC21352; NAG22

Clonality

Monoclonal,Recombinant

Clone

7C5

Conjugation

Unconjugated

Applications

WB

Field of Research

Signal Transduction; Cardiovascular

Purification

Protein A

Concentration

0.2 mg/mL

Dilution

WB 1:2000-1:10000

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

93 kDa

Observed Molecular Weight

70 kDa

Isotype

IgG, κ

Available Sizes

Curated Selection

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