Recombinant Caldesmon Monoclonal Antibody
Product Specifications
Background
This gene encodes a calmodulin- and actin-binding protein that plays an essential role inThe regulation of smooth muscle and nonmuscle contraction.The conserved domain of this protein possessesThe binding activities to Ca (2+) -calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor ofThe actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca (2+) -dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.
Abbreviation
Caldesmon
UniProt
Q05682
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant Human Caldesmon protein
Target
NAG; MGC; CALD1; CDM; H-CAD; HCAD; L-CAD; LCAD; NAG22; caldesmon; CALD 1; Caldesmon 1; Caldesmon 1 Isoform 1; Caldesmon 1 Isoform 2; Caldesmon 1 Isoform 3; Caldesmon 1 Isoform 4; Caldesmon 1 Isoform 5; Caldesmon1; H CAD; L CAD; MGC21352; CAD; CAD; CALD 1; CALD1; CALD1; Caldesmon 1; Caldesmon 1 Isoform 1; Caldesmon 1 Isoform 2; Caldesmon 1 Isoform 3; Caldesmon 1 Isoform 4; Caldesmon 1 Isoform 5; Caldesmon; Caldesmon1; CDM; H CAD; HCAD; L CAD; LCAD; MGC21352; NAG22
Clonality
Monoclonal,Recombinant
Clone
7C5
Conjugation
Unconjugated
Applications
WB
Field of Research
Signal Transduction; Cardiovascular
Purification
Protein A
Concentration
0.2 mg/mL
Dilution
WB 1:2000-1:10000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
93 kDa
Observed Molecular Weight
70 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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