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Recombinant Cardiac Troponin I Monoclonal Antibody

Product Specifications

Background

Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that formThe troponin complex ofThe thin filaments of striated muscle. TnI isThe inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation.The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodesThe TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM) .

Abbreviation

Cardiac Troponin I

UniProt

P19429

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Recombinant Human Cardiac Troponin I protein

Target

CMH; RCM; TNNI; TNNC; troponin I; TNNI3; CMD1FF; CMD2A; CMH7; RCM1; TNNC1; cTnI; troponin I3; Troponin I-C

Clonality

Monoclonal,Recombinant

Clone

7C4

Conjugation

Unconjugated

Applications

WB

Field of Research

Signal Transduction; Stem Cells; Cardiovascular; Developmental Biology

Purification

Protein A

Concentration

0.2 mg/mL

Dilution

WB 1:2000-1:10000

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Product MSDS

https://789.bio/eb/K2ez99fV

Calculated Molecular Weight

24 kDa

Observed Molecular Weight

24 kDa

Isotype

IgG, κ

Available Sizes

Curated Selection

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