Recombinant BRG1 Monoclonal Antibody

The protein encoded by this gene is a member ofThe SWI/SNF family of proteins and is similar toThe brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by alteringThe chromatin structure around those genes.The encoded protein is part ofThe large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulateThe expression ofThe tumorigenic protein CD44. Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2. Multiple transcript variants encoding different isoforms have been found for this gene.

BRG; SNF; CSS; BAF; MRD; SWI; RTPS; SNF2L; SMARCA; BAF190; BAF190A; BRG1; CSS4; MRD16; RTPS2; SNF2; SNF2L4; SNF2LB; SWI2; hSNF2b; SMARCA4; SNF2B; actin dependent regulator of chromatin; ATP dependent helicase SMARCA4; ATP-dependent helicase SMARCA4; BAF 190; Brahma protein like 1; BRG1 associated factor 190A; BRG1 protein; BRG1-associated factor 190A; BRM/SWI2 related gene 1; Global transcription activator homologous sequence; global transcription activator snf2l4; Homeotic gene regulator; matrix associated; member 4; Mitotic growth and transcription activator; Nuclear protein GRB1; Protein brahma homolog 1; Protein BRG1; Protein BRG-1; SMARC A4; SMCA4; SNF2 beta; SNF2 like 4; SNF2-beta; subfamily a; Sucrose nonfermenting like 4; SWI/SNF related; SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily A member 4; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4; Transcription activator BRG1