Recombinant Keap1 Monoclonal Antibody
Product Specifications
Background
KEAP1 (kelch like ECH associated protein 1) Homo sapiens This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene.
Abbreviation
Keap1
UniProt
Q14145
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant Human Keap1 protein
Target
INrf; KLHL; KIAA; KEAP1; INrf2; KLHL19; KEAP-1; KIAA0132; Cytosolic inhibitor of Nrf2; INrf 2; Keap 1; kelch like ECH associated protein 1; Kelch like family member 19; Kelch like protein 19; Kelch-like ECH-associated protein 1; Kelch-like protein 19; KLHL 19; MGC10630; MGC1114; MGC20887; MGC4407; MGC9454
Clonality
Monoclonal,Recombinant
Clone
9B10
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Epigenetics and Nuclear Signaling
Purification
Protein A
Concentration
0.2 mg/mL
Dilution
IHC 1:200-1:1000; WB 1:2000-1:10000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
70 kDa
Observed Molecular Weight
60-70 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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