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Recombinant Keap1 Monoclonal Antibody

Product Specifications

Background

KEAP1 (kelch like ECH associated protein 1) Homo sapiens This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene.

Abbreviation

Keap1

UniProt

Q14145

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Recombinant Human Keap1 protein

Target

INrf; KLHL; KIAA; KEAP1; INrf2; KLHL19; KEAP-1; KIAA0132; Cytosolic inhibitor of Nrf2; INrf 2; Keap 1; kelch like ECH associated protein 1; Kelch like family member 19; Kelch like protein 19; Kelch-like ECH-associated protein 1; Kelch-like protein 19; KLHL 19; MGC10630; MGC1114; MGC20887; MGC4407; MGC9454

Clonality

Monoclonal,Recombinant

Clone

9B10

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Epigenetics and Nuclear Signaling

Purification

Protein A

Concentration

0.2 mg/mL

Dilution

IHC 1:200-1:1000; WB 1:2000-1:10000

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

70 kDa

Observed Molecular Weight

60-70 kDa

Isotype

IgG, κ

Available Sizes

Curated Selection

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