Recombinant ATG5 Monoclonal Antibody

The protein encoded by this gene, in combination with autophagy protein 12, functions as an E1-like activating enzyme in a ubiquitin-like conjugating system. The encoded protein is involved in several cellular processes, including autophagic vesicle formation, mitochondrial quality control after oxidative damage, negative regulation of the innate antiviral immune response, lymphocyte development and proliferation, MHC II antigen presentation, adipocyte differentiation, and apoptosis. Several transcript variants encoding different protein isoforms have been found for this gene.

ATG; APG; hAPG; Autophagy protein; ATG5; APG5; APG5-LIKE; APG5L; ASP; hAPG5; Apoptosis-specific protein; Autophagy protein 5; APG 5; APG 5L; APG5 autophagy 5 like; APG5 like; Apoptosis specific protein; ATG 5; ATG5 autophagy related 5 homolog; Autophagy related 5; Homolog of S Cerevisiae autophagy 5; OTTHUMP00000040507