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Recombinant HMGB1 Monoclonal Antibody

Product Specifications

Background

HMGB1 (high mobility group box 1) Homo sapiens. This gene encodes a protein that belongs to the High Mobility Group-box superfamily. The encoded non-histone, nuclear DNA-binding protein regulates transcription, and is involved in organization of DNA. This protein plays a role in several cellular processes, including inflammation, cell differentiation and tumor cell migration. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants that encode the same protein.

Abbreviation

HMGB1

UniProt

P09429

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Recombinant Human HMGB1 protein

Target

SBP; HMGB; High Mobility Group Protein; High mobility group protein B; HMG; HMG-1; HMG1; HMG3; SBP-1; HMGB1; Amphoterin; High Mobility Group Protein 1; High mobility group protein B1; High mobility group protein 1 (HMG-1) ; High mobility group protein 1; high mobility group protein B1; high-mobility group box 1; HMG1; HMG-1; HMG1DKFZp686A04236; HMG3; HMGB1; SBP-1; Chromosomal protein; DKFZp686A04236; High mobility group 1; High mobility group box 1; high-mobility group (nonhistone chromosomal) protein 1; HMGB 1; nonhistone; NONHISTONE CHROMOSOMAL PROTEIN HMG1; SBP 1; Sulfoglucuronyl carbohydrate binding protein

Clonality

Monoclonal,Recombinant

Clone

7B7

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Epigenetics and Nuclear Signaling

Purification

Protein A

Concentration

0.2 mg/mL

Dilution

IHC 1:2000-1:10000; WB 1:5000-1:10000

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

25 kDa

Observed Molecular Weight

25 kDa

Isotype

IgG, κ

Available Sizes

Curated Selection

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