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Recombinant ERK1/2 Monoclonal Antibody

Product Specifications

Background

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described.

Abbreviation

ERK1/2

UniProt

P28482, P27361

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Recombinant Human ERK1/2 protein

Target

ERK; MAPK1/MAPK; MAPK; MAPK1/MAPK3; ERK2; PRKM1; PRKM2; MAPK1; ERK 2; ERK-2; ERT1; Extracellular Signal Regulated Kinase 2; Extracellular signal-regulated kinase 2; MAP kinase 1; MAP kinase 2; MAP kinase isoform p42; MAPK 1; MAPK 2; MAPK2; mitogen-activated; mitogen-activated protein kinase 1; Mitogen-activated protein kinase 2; MK01; p38; p40; p41; p41mapk; P42MAPK; p42-MAPK; protein kinase; protein tyrosine kinase ERK2; ERK 1/2

Clonality

Monoclonal,Recombinant

Clone

7B3

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Neuroscience; Signal Transduction; Stem Cells; Cancer

Purification

Protein A

Concentration

0.2 mg/mL

Dilution

IHC 1:2000-1:10000; WB 1:2000-1:10000

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

43 kDa,41 kDa

Observed Molecular Weight

43 kDa,41 kDa

Isotype

IgG, κ

Available Sizes

Frequently Asked Questions

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