Recombinant ERK1/2 Monoclonal Antibody
Product Specifications
Background
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described.
Abbreviation
ERK1/2
UniProt
P28482, P27361
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant Human ERK1/2 protein
Target
ERK; MAPK1/MAPK; MAPK; MAPK1/MAPK3; ERK2; PRKM1; PRKM2; MAPK1; ERK 2; ERK-2; ERT1; Extracellular Signal Regulated Kinase 2; Extracellular signal-regulated kinase 2; MAP kinase 1; MAP kinase 2; MAP kinase isoform p42; MAPK 1; MAPK 2; MAPK2; mitogen-activated; mitogen-activated protein kinase 1; Mitogen-activated protein kinase 2; MK01; p38; p40; p41; p41mapk; P42MAPK; p42-MAPK; protein kinase; protein tyrosine kinase ERK2; ERK 1/2
Clonality
Monoclonal,Recombinant
Clone
7B3
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Neuroscience; Signal Transduction; Stem Cells; Cancer
Purification
Protein A
Concentration
0.2 mg/mL
Dilution
IHC 1:2000-1:10000; WB 1:2000-1:10000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
43 kDa,41 kDa
Observed Molecular Weight
43 kDa,41 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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