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Recombinant Phospho-mTOR (Ser2448) Monoclonal Antibody

Product Specifications

Background

The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene.

Abbreviation

MTOR

UniProt

P42345

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

A synthetic peptide corresponding to residues around (Ser2448) of Human Phospho-mTOR

Target

RAFT; RAPT; FK506 binding protein 12-rapamycin associated protein; FRAP; FRAP1; FRAP2; RAFT1; RAPT1; SKS; mTOR; FK506 binding protein 12-rapamycin associated protein 1; Mechanistic target of rapamycin; dJ576K7.1 (FK506 binding protein 12 rapamycin associated protein 1) ; FK506 binding protein 12 rapamycin associated protein 1; FK506 binding protein 12 rapamycin associated protein 2; FK506 binding protein 12 rapamycin complex associated protein 1; FK506-binding protein 12-rapamycin complex-associated protein 1; FKBP rapamycin associated protein; FKBP12 rapamycin complex associated protein; FKBP12-rapamycin complex-associated protein; FKBP12-rapamycin complex-associated protein 1; FLJ44809; Mammalian target of rapamycin; OTTHUMP00000001983; Rapamycin and FKBP12 target 1; Rapamycin associated protein FRAP2; Rapamycin target protein; Rapamycin target protein 1; Serine/threonine-protein kinase mTOR

Clonality

Monoclonal,Recombinant

Clone

6B4

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Cell Biology; Epigenetics and Nuclear Signaling; Cancer; Cardiovascular; Kits; Lysates; Other; Metabolism

Purification

Protein A

Concentration

0.2 mg/mL

Dilution

IHC 1:500-1:2000; WB 1:2000-1:10000

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

289 kDa

Observed Molecular Weight

250 kDa

Isotype

IgG, κ

Available Sizes

Curated Selection

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