Recombinant EGFR Monoclonal Antibody
Product Specifications
Background
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.
Abbreviation
EGFR
UniProt
P00533
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant Human EGFR protein
Target
PIG; HER; Proto-oncogene c-ErbB; Receptortyrosine-protein kinase erbB; Receptor tyrosine-protein kinase erbB; NISBD; EGFR; ERBB; ERBB1; HER1; NISBD2; PIG61; mENA; ErbB-1; Receptortyrosine-protein kinase erbB-1; Epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1; NISBD2; epidermal growth factor receptor; ERBB; ERBB1; HER1; mENA; NISBD2; PIG61; Avian erythroblastic leukemia viral (v erb b) oncogene homolog; Cell growth inhibiting protein 40; Cell proliferation inducing protein 61; EGF R; Epidermal growth factor receptor (avian erythroblastic leukemia viral (v erb b) oncogene homolog) ; Epidermal growth factor receptor (erythroblastic leukemia viral (v erb b) oncogene homolog avian) ; ErbB1; ERBB; erb-b2 receptor tyrosine kinase 1; Errp; Oncogen ERBB; Receptor tyrosine protein kinase ErbB 1; SA7; Species antigen 7; Urogastrone; v-erb-b Avian erythroblastic leukemia viral oncogen homolog; wa2; Wa5
Clonality
Monoclonal,Recombinant
Clone
5H2
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Signal Transduction; Cancer
Purification
Protein A
Concentration
0.2 mg/mL
Dilution
IHC 1:200-1:1000; WB 1:2000-1:10000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Product MSDS
https://789.bio/eb/xrWTZv0D
Calculated Molecular Weight
134 kDa
Observed Molecular Weight
175 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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