Recombinant Bak Monoclonal Antibody

The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.

CDN; BCL2L; BAK1; BAK; BAK-LIKE; BCL2L7; CDN1; Apoptosis regulator BAK; BAK like; Bak NT; Bcl 2 homologous antagonist/killer; Bcl 2 like 7 protein; BCL2 antagonist/killer 1; Bcl-2 Homologous Antagonist/Killer; Bcl2 like 7 Protein; Bcl2-L-7; Bcl-2-like protein 7; Cell death inhibitor 1; MGC117255; MGC3887; NBak; Pro apoptotic protein BAK