Recombinant Rpb1 Monoclonal Antibody
Product Specifications
Background
This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA.
Abbreviation
Rpb1
UniProt
P24928
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant Human Rpb1 protein
Target
RPB; RPO; POLR; RPBh; RPOL; hRPB; hsRPB; POLR2A; POLR2; POLRA; RPB1; RPBh1; RPO2; RPOL2; RpIILS; hRPB220; hsRPB1; Pol II
Clonality
Monoclonal,Recombinant
Clone
5B5
Conjugation
Unconjugated
Applications
WB
Field of Research
Epigenetics and Nuclear Signaling
Purification
Protein A
Concentration
0.2 mg/mL
Dilution
WB 1:2000-1:10000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
192 kDa
Observed Molecular Weight
250 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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