Recombinant HDAC4 Monoclonal Antibody
Product Specifications
Background
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.
Abbreviation
HDAC4
UniProt
P56524
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant Human HDAC4 protein
Target
AHO; KIAA; EC 3.5.1.; Histone deacetylase; HDAC4; AHO3; BDMR; HA6116; HD4; HDAC-4; HDAC-A; HDACA; EC 3.5.1.98; HD 4; HDAC 4; HDAC A; Histone deacetylase 4; Histone Deacetylase A; KIAA0288
Clonality
Monoclonal,Recombinant
Clone
4B8
Conjugation
Unconjugated
Applications
WB
Field of Research
Stem Cells; Epigenetics and Nuclear Signaling; Cardiovascular; Neuroscience
Purification
Protein A
Concentration
0.2 mg/mL
Dilution
WB 1:2000-1:10000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
119 kDa
Observed Molecular Weight
140 kDa
Isotype
IgG, κ
Available Sizes
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