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Recombinant Raptor Monoclonal Antibody

Product Specifications

Background

This gene encodes a component of a signaling pathway that regulates cell growth in response to nutrient and insulin levels. The encoded protein forms a stoichiometric complex with the mTOR kinase, and also associates with eukaryotic initiation factor 4E-binding protein-1 and ribosomal protein S6 kinase. The protein positively regulates the downstream effector ribosomal protein S6 kinase, and negatively regulates the mTOR kinase. Multiple transcript variants encoding different isoforms have been found for this gene.

Abbreviation

Raptor

UniProt

Q8N122

Host

Rabbit

Reactivity

Human; Mouse

Immunogen

Recombinant Human Raptor protein

Target

KOG; Mip; KIAA; KOG1; Mip1; RPTOR; regulatory-associated protein of mTOR; KIAA1303; RAPTOR; KOG1; Mip1; regulatory-associated protein of mTOR

Clonality

Monoclonal,Recombinant

Clone

5D14

Conjugation

Unconjugated

Applications

WB

Field of Research

Cell Biology; Signal Transduction; Epigenetics and Nuclear Signaling

Purification

Protein A

Concentration

0.2 mg/mL

Dilution

WB 1:1000-1:5000

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

149 kDa

Observed Molecular Weight

149 kDa

Isotype

IgG, κ

Available Sizes

Frequently Asked Questions

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