Recombinant Raptor Monoclonal Antibody
Product Specifications
Background
This gene encodes a component of a signaling pathway that regulates cell growth in response to nutrient and insulin levels. The encoded protein forms a stoichiometric complex with the mTOR kinase, and also associates with eukaryotic initiation factor 4E-binding protein-1 and ribosomal protein S6 kinase. The protein positively regulates the downstream effector ribosomal protein S6 kinase, and negatively regulates the mTOR kinase. Multiple transcript variants encoding different isoforms have been found for this gene.
Abbreviation
Raptor
UniProt
Q8N122
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Recombinant Human Raptor protein
Target
KOG; Mip; KIAA; KOG1; Mip1; RPTOR; regulatory-associated protein of mTOR; KIAA1303; RAPTOR; KOG1; Mip1; regulatory-associated protein of mTOR
Clonality
Monoclonal,Recombinant
Clone
5D14
Conjugation
Unconjugated
Applications
WB
Field of Research
Cell Biology; Signal Transduction; Epigenetics and Nuclear Signaling
Purification
Protein A
Concentration
0.2 mg/mL
Dilution
WB 1:1000-1:5000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
149 kDa
Observed Molecular Weight
149 kDa
Isotype
IgG, κ
Available Sizes
Frequently Asked Questions
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