Recombinant Granzyme B Monoclonal Antibody
Product Specifications
Background
This gene encodes a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing. Expression of this gene may be elevated in human patients with cardiac fibrosis.
Abbreviation
Granzyme B
UniProt
P10144
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant Human Granzyme B protein
Target
CTLA; Cathepsin G-like; CTSGL; Granzyme; CGL; C11; CCPI; CGL-1; CGL1; CSP-B; CSPB; CTLA1; CTSGL1; HLP; SECT; Granzyme B; GZMB; Cathepsin G-like 1; Granzyme 2; GZM-B; T-cell serine protease 1-3E; GRB; C11; CCPI; CGL-1; CGL1; CSP-B; CSPB; CTLA1; CTSGL1; HLP; SECT; Granzyme B; GZMB
Clonality
Monoclonal,Recombinant
Clone
5D12
Conjugation
Unconjugated
Applications
WB
Field of Research
Cell Biology; Immunology
Purification
Protein A
Concentration
0.2 mg/mL
Dilution
WB 1:2000-1:10000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
28 kDa
Observed Molecular Weight
37 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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