Recombinant CD89 Monoclonal Antibody
Product Specifications
Background
This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Abbreviation
CD89
UniProt
P24071
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant Human CD89 protein
Target
XXbac-BPG230H; CTB-61M; FCAR; CD89; CTB-61M7.2; FcalphaRI; Fc alpha receptor; Fc fragment of IgA; IgA Fc Receptor; Immunoglobulin Alpha Fc Receptor; receptor for; XXbac-BPG230H20.5; IgA R; Fc fragment of IgA receptor
Clonality
Monoclonal,Recombinant
Clone
11G5
Conjugation
Unconjugated
Applications
WB
Field of Research
Immunology
Purification
Protein A
Concentration
0.2 mg/mL
Dilution
WB 1:1000-5000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Product MSDS
https://789.bio/eb/ZbqlIVgg
Observed Molecular Weight
32 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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