Recombinant CD89 Monoclonal Antibody

This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.

XXbac-BPG230H; CTB-61M; FCAR; CD89; CTB-61M7.2; FcalphaRI; Fc alpha receptor; Fc fragment of IgA; IgA Fc Receptor; Immunoglobulin Alpha Fc Receptor; receptor for; XXbac-BPG230H20.5; IgA R; Fc fragment of IgA receptor