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Recombinant IKB epsilon Monoclonal Antibody

Product Specifications

Background

The protein encoded by this gene binds to components of NF-kappa-B, trapping the complex in the cytoplasm and preventing it from activating genes in the nucleus. Phosphorylation of the encoded protein targets it for destruction by the ubiquitin pathway, which activates NF-kappa-B by making it available to translocate to the nucleus.

Abbreviation

IKB epsilon

UniProt

O00221

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant Human IKB epsilon protein

Target

NFKBIE; IKBE; IκB-ε

Clonality

Monoclonal,Recombinant

Clone

11G1

Conjugation

Unconjugated

Applications

WB

Field of Research

Signal Transduction; Epigenetics and Nuclear Signaling; Immunology

Purification

Protein A

Concentration

0.2 mg/mL

Dilution

WB 1:1000-5000

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Observed Molecular Weight

55 kDa

Isotype

IgG, κ

Available Sizes

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