Recombinant MMP2 Monoclonal Antibody

Matrix metallopeptidase 2 (MMP2) Homo sapiens This gene is a member of the matrix metalloproteinase (MMP) gene family, that are zinc-dependent enzymes capable of cleaving components of the extracellular matrix and molecules involved in signal transduction. The protein encoded by this gene is a gelatinase A, type IV collagenase, that contains three fibronectin type II repeats in its catalytic site that allow binding of denatured type IV and V collagen and elastin. Unlike most MMP family members, activation of this protein can occur on the cell membrane. This enzyme can be activated extracellularly by proteases, or, intracellulary by its S-glutathiolation with no requirement for proteolytical removal of the pro-domain. This protein is thought to be involved in multiple pathways including roles in the nervous system, endometrial menstrual breakdown, regulation of vascularization, and metastasis.

TBE; CLG; Matrix Metalloproteinase; MMP; CLG4; CLG4A; MMP-2; MMP-II; MONA; TBE-1; MMP2;72 kDa Gelatinase;72 kDa Type IV Collagenase; Gelatinase A; Matrix Metalloproteinase-2;72kD type IV collagenase;72kDa gelatinase;72kDa type IV collagenase) ; CLG 4; CLG 4A; Collagenase Type 4 alpha; Collagenase type IV A; Gelatinase alpha; Gelatinase neutrophil; Matrix metallopeptidase 2 gelatinase A 72kDa gelatinase 72kDa type IV collagenase; Matrix Metalloproteinase 2; Matrix metalloproteinase 2 (gelatinase A; Matrix metalloproteinase II; MMP 2; MMP II; Neutrophil gelatinase; PEX; TBE 1; MMP-2