Recombinant BTK Monoclonal Antibody
Product Specifications
Background
The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.
Abbreviation
Btk
UniProt
Q06187
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant Human BTK protein
Target
IMD; AGMX; PSCTK; AGMX1; AT; ATK; BPK; IMD1; PSCTK1; XLA; BTK; Bruton tyrosine kinase; AGMX1; ATK; BPK; Bruton tyrosine kinase; IMD1; PSCTK1; XLA
Clonality
Monoclonal,Recombinant
Clone
11D12
Conjugation
Unconjugated
Applications
WB
Field of Research
Signal Transduction; Immunology
Purification
Protein A
Concentration
0.2 mg/mL
Dilution
WB 1:2000-1:10000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
67 kDa
Observed Molecular Weight
67 kDa
Isotype
IgG, κ
Available Sizes
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