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Recombinant GPER1 Monoclonal Antibody

Product Specifications

Background

This gene is a member of the G-protein coupled receptor 1 family and encodes a multi-pass membrane protein that localizes to the endoplasmic reticulum. The protein binds estrogen, resulting in intracellular calcium mobilization and synthesis of phosphatidylinositol 3,4,5-trisphosphate in the nucleus. This protein therefore plays a role in the rapid nongenomic signaling events widely observed following stimulation of cells and tissues with estrogen. Alternate transcriptional splice variants which encode the same protein have been characterized.

Abbreviation

GPER1

UniProt

Q99527

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Recombinant Human GPER1 protein

Target

FEG; GPR; DRY; G protein-coupled receptor; CMKRL; GPER1; CEPR; CMKRL2; DRY12; FEG-1; GPCR-Br; GPER; GPR30; LERGU; LERGU2; LyGPR; mER; G protein-coupled receptor 30

Clonality

Monoclonal,Recombinant

Clone

6A6

Conjugation

Unconjugated

Applications

WB

Field of Research

Neuroscience; Signal Transduction; Epigenetics and Nuclear Signaling; Metabolism

Purification

Protein A

Concentration

0.2 mg/mL

Dilution

WB 1:2000-1:10000

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Product MSDS

https://789.bio/eb/AEsi09W9

Calculated Molecular Weight

42 kDa

Observed Molecular Weight

55 kDa

Isotype

IgG, κ

Available Sizes

Curated Selection

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