Recombinant GPER1 Monoclonal Antibody
Product Specifications
Background
This gene is a member of the G-protein coupled receptor 1 family and encodes a multi-pass membrane protein that localizes to the endoplasmic reticulum. The protein binds estrogen, resulting in intracellular calcium mobilization and synthesis of phosphatidylinositol 3,4,5-trisphosphate in the nucleus. This protein therefore plays a role in the rapid nongenomic signaling events widely observed following stimulation of cells and tissues with estrogen. Alternate transcriptional splice variants which encode the same protein have been characterized.
Abbreviation
GPER1
UniProt
Q99527
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant Human GPER1 protein
Target
FEG; GPR; DRY; G protein-coupled receptor; CMKRL; GPER1; CEPR; CMKRL2; DRY12; FEG-1; GPCR-Br; GPER; GPR30; LERGU; LERGU2; LyGPR; mER; G protein-coupled receptor 30
Clonality
Monoclonal,Recombinant
Clone
6A6
Conjugation
Unconjugated
Applications
WB
Field of Research
Neuroscience; Signal Transduction; Epigenetics and Nuclear Signaling; Metabolism
Purification
Protein A
Concentration
0.2 mg/mL
Dilution
WB 1:2000-1:10000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
42 kDa
Observed Molecular Weight
55 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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