Recombinant BMAL1 Monoclonal Antibody

The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This heterodimer binds E-box enhancer elements upstream of Period (PER1, PER2, PER3) and Cryptochrome (CRY1, CRY2) genes and activates transcription of these genes. PER and CRY proteins heterodimerize and repress their own transcription by interacting in a feedback loop with CLOCK/ARNTL complexes. Defects in this gene have been linked to infertility, problems with gluconeogenesis and lipogenesis, and altered sleep patterns. Several transcript variants encoding different isoforms have been found for this gene.

JAP; MOP; MIC; Pgp; CDW; BMAL; PASD; CSPG; bHLHe; MDU; ARNTL; BMAL1; BMAL1c; JAP3; MOP3; PASD3; TIC; bHLHe5; aryl hydrocarbon receptor nuclear translocator like; IN; LHR; MC56; MDU2; MDU3; MIC4; Pgp1; CDW44; CSPG8; HCELL; HUTCH-I; ECMR-III; ARNT like protein 1 brain and muscle; Aryl hydrocarbon receptor nuclear translocator like protein 1; Aryl hydrocarbon receptor nuclear translocator-like protein 1; Basic helix loop helix PAS orphan MOP3; Basic helix loop helix PAS protein MOP3; Basic-helix-loop-helix-PAS protein MOP3; bHLH PAS protein JAP3; bHLH-PAS protein JAP3; BMAL 1; Brain and muscle ARNT like 1; Brain and muscle ARNT-like 1; CG8727 PA; Class E basic helix-loop-helix protein 5; cycle; JAP 3; Member of PAS protein 3; Member of PAS superfamily 3; MGC47515; MOP 3; PAS domain-containing protein 3; PASD 3