Recombinant STAT2 Monoclonal Antibody
Product Specifications
Background
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. Multiple transcript variants encoding different isoforms have been found for this gene.
Abbreviation
Stat2
UniProt
P52630
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant Human STAT2 protein
Target
IMD; ISGF; STAT2; IMD44; ISGF-3; P113; STAT113; Homo sapiens interferon alpha induced transcriptional activator; interferon alpha induced transcriptional activator; ISGF 3; ISGF3; MGC59816; signal transducer and activator of transcription 2; signal transducer and activator of transcription 2 113kD
Clonality
Monoclonal,Recombinant
Clone
6G8
Conjugation
Unconjugated
Applications
WB
Field of Research
Signal Transduction; Epigenetics and Nuclear Signaling
Purification
Protein A
Concentration
0.2 mg/mL
Dilution
WB 1:2000-1:10000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Product MSDS
https://789.bio/eb/UFZfq239
Calculated Molecular Weight
98 kDa
Observed Molecular Weight
113 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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