Recombinant Phospho-YAP (Ser127) Monoclonal Antibody
Product Specifications
Background
This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.
Abbreviation
YAP
UniProt
P46937
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
A synthetic peptide corresponding to residues around (Ser127) of Human Phospho-YAP
Target
COB; COB1; YAP; YAP2; YAP65; YKI; YAP1;65 kDa Yes associated protein;65 kDa Yes-associated protein; Basic protease inhibitor; BPTI; Pancreatic Trypsin Inhibitor; Trasylol; YAp 1; YAP 65; Yes associated protein 1; Yes associated protein 1 65kDa; Yes associated protein 2; yes associated protein beta; yes -associated protein delta; Yorkie homolog
Clonality
Monoclonal,Recombinant
Clone
1F13
Conjugation
Unconjugated
Applications
WB
Field of Research
Signal Transduction; Epigenetics and Nuclear Signaling; Cancer
Purification
Protein A
Concentration
0.2 mg/mL
Dilution
WB 1:2000-1:10000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
55 kDa
Observed Molecular Weight
55 kDa
Isotype
IgG, κ
Available Sizes
Frequently Asked Questions
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