Recombinant Phospho-SMAD5 (Ser463, Ser465) Monoclonal Antibody
Product Specifications
Background
The protein encoded by this gene is involved in the transforming growth factor beta signaling pathway that results in an inhibition of the proliferation of hematopoietic progenitor cells. The encoded protein is activated by bone morphogenetic proteins type 1 receptor kinase, and may be involved in cancer. Alternative splicing results in multiple transcript variants.
Abbreviation
Smad5
UniProt
Q99717
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
A synthetic peptide corresponding to residues around (Ser463, Ser465) of Human Phospho-SMAD5
Target
JV5; MADH; SMAD; DWFC; JV5-1; MADH5; SMAD5
Clonality
Monoclonal,Recombinant
Clone
9F5
Conjugation
Unconjugated
Applications
WB
Field of Research
Signal Transduction; Epigenetics and Nuclear Signaling; Stem Cells; Developmental Biology; Cancer; Kits; Lysates; Other; Metabolism
Purification
Protein A
Concentration
0.2 mg/mL
Dilution
WB 1:2000-1:10000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
52 kDa
Observed Molecular Weight
60 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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