Recombinant Cleaved N-terminal GSDMD Monoclonal Antibody
Product Specifications
Background
GSDMD is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. GSDMD has been suggested to act as a tumor suppressor. Recently, GSDMD is identified as a new component of inflammasomes, and it is an executor of pyroptosis and required for interleukin-1β secretion. Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death.
Abbreviation
Cleaved N-terminal GSDMD
UniProt
P57764
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant Human Cleaved N-terminal GSDMD protein
Target
FKSG; GSDMDC; DF5L; DFNA5L; FKSG10; GSDMDC1; GSDMD; GSDMD
Clonality
Monoclonal,Recombinant
Clone
8D10
Conjugation
Unconjugated
Applications
WB
Field of Research
Cell Biology
Purification
Protein A
Concentration
0.2 mg/mL
Dilution
WB 1:2000-1:10000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
53 kDa
Observed Molecular Weight
35 kDa
Isotype
IgG, κ
Available Sizes
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