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Recombinant TTF1 Monoclonal Antibody

Product Specifications

Background

This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares the symbol/alias 'TTF1' with another gene, transcription termination factor 1, which plays a role in ribosomal gene transcription.

Abbreviation

TTF1

UniProt

P43699

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Recombinant Human TTF1 protein

Target

NKX; NMTC; TITF; NKX2-; TTF; NKX2-1; BCH; BHC; NK-2; NKX2.1; NKX2A; NMTC1; T/EBP; TEBP; TITF1; TTF-1; TTF1; AV026640; Benign chorea; drosophila; Homeobox protein NK 2 homolog A; Homeobox protein NK-2 homolog A; Homeobox protein Nkx 2.1; Homeobox protein Nkx2.1; Homeobox protein Nkx-2.1; homolog of; mouse; NK 2; NK 2 homolog A; NK2; NK2 homeobox 1; NK2.1; Nkx 2 1; NKX 2.1; NKX 2A; NKX2 1; NKX21; T EBP; Thyroid nuclear factor; Thyroid nuclear factor 1; Thyroid specific enhancer binding protein; Thyroid transcription factor 1; Tin man; Tinman; TITF 1; TTF 1; BCH; BHC; Nkx2-1; NKX2.1; NKX2A; T/EBP; TEBP; TITF1; TTF-1; TTF1; TTF-1

Clonality

Monoclonal,Recombinant

Clone

8D7

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Epigenetics and Nuclear Signaling

Purification

Protein A

Concentration

0.2 mg/mL

Dilution

IHC 1:200-1:1000; WB 1:2000-1:10000

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

40 kDa

Observed Molecular Weight

40 kDa

Isotype

IgG, κ

Available Sizes

Frequently Asked Questions

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