Recombinant TTF1 Monoclonal Antibody
Product Specifications
Background
This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares the symbol/alias 'TTF1' with another gene, transcription termination factor 1, which plays a role in ribosomal gene transcription.
Abbreviation
TTF1
UniProt
P43699
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant Human TTF1 protein
Target
NKX; NMTC; TITF; NKX2-; TTF; NKX2-1; BCH; BHC; NK-2; NKX2.1; NKX2A; NMTC1; T/EBP; TEBP; TITF1; TTF-1; TTF1; AV026640; Benign chorea; drosophila; Homeobox protein NK 2 homolog A; Homeobox protein NK-2 homolog A; Homeobox protein Nkx 2.1; Homeobox protein Nkx2.1; Homeobox protein Nkx-2.1; homolog of; mouse; NK 2; NK 2 homolog A; NK2; NK2 homeobox 1; NK2.1; Nkx 2 1; NKX 2.1; NKX 2A; NKX2 1; NKX21; T EBP; Thyroid nuclear factor; Thyroid nuclear factor 1; Thyroid specific enhancer binding protein; Thyroid transcription factor 1; Tin man; Tinman; TITF 1; TTF 1; BCH; BHC; Nkx2-1; NKX2.1; NKX2A; T/EBP; TEBP; TITF1; TTF-1; TTF1; TTF-1
Clonality
Monoclonal,Recombinant
Clone
8D7
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Epigenetics and Nuclear Signaling
Purification
Protein A
Concentration
0.2 mg/mL
Dilution
IHC 1:200-1:1000; WB 1:2000-1:10000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
40 kDa
Observed Molecular Weight
40 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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