Recombinant Synuclein-α Monoclonal Antibody

Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene.

Fetal liver kinase; Protein-tyrosine kinase receptor flk; Vascular endothelial growth factor receptor; PD1; NACP; PARK1; PARK4; SNCA; SNC-A; aSYN; CD309; Fetal liver kinase 1; FLK1; FLK-1; KDR; Kinase insert domain receptor; Protein-tyrosine kinase receptor flk-1; Vascular endothelial growth factor receptor 2; VEGFR; VEGFR2; VEGFR-2; Alpha-synuclein; Non-A beta component of AD amyloid; Non-A4 component of amyloid precursor; PARK1; alpha (non A4 component of amyloid precursor) ; Alpha synuclein; alphaSYN; isoform NACP140; Lewy body) 4; MGC105443; MGC110988; MGC127560; MGC64356; Non A beta component of AD amyloid; Non A4 component of amyloid; Non A4 component of amyloid precursor; Non-A4 component of amyloid; Non-A-beta component of alzheimers disease amyloid; OTTHUMP00000218549; OTTHUMP00000218551; OTTHUMP00000218552; OTTHUMP00000218553; OTTHUMP00000218554; PARK 1; PARK 4; Parkinson disease (autosomal dominant; Parkinson disease familial 1; precursor of; Snca synuclein; SYN; Synuclein; Synuclein alpha; Synuclein alpha 140; SYUA