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Recombinant Phospho-CREB-1 (Ser133) Monoclonal Antibody

Product Specifications

Background

This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in several transcript variants encoding different isoforms.

Abbreviation

CREB-1

UniProt

P16220

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

A synthetic peptide corresponding to residues around (Ser133) of Human Phospho-CREB-1

Target

CREB1; CREB; CREB-1; Active transcription factor CREB; cAMP response element binding protein; cAMP response element binding protein 1; cAMP responsive element binding protein 1; cAMP-responsive element-binding protein 1; Cyclic AMP-responsive element-binding protein 1; MGC9284; OTTHUMP00000163864; OTTHUMP00000163865; OTTHUMP00000206660; OTTHUMP00000206662; OTTHUMP00000206667; Transactivator protein

Clonality

Monoclonal,Recombinant

Clone

3P8

Conjugation

Unconjugated

Applications

WB

Field of Research

Epigenetics and Nuclear Signaling; Immunology; Signal Transduction

Purification

Protein A

Concentration

0.2 mg/mL

Dilution

WB 1:2000-1:10000

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

37 kDa

Observed Molecular Weight

43 kDa

Isotype

IgG, κ

Available Sizes

Frequently Asked Questions

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