Recombinant RAGE Monoclonal Antibody
Product Specifications
Background
The advanced glycosylation end product (AGE) receptor encoded by this gene is a member of the immunoglobulin superfamily of cell surface receptors. It is a multiligand receptor, and besides AGE, interacts with other molecules implicated in homeostasis, development, and inflammation, and certain diseases, such as diabetes and Alzheimer's disease. Many alternatively spliced transcript variants encoding different isoforms, as well as non-protein-coding variants, have been described for this gene (PMID:18089847) .
Abbreviation
RAGE
UniProt
Q15109
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant Human RAGE protein
Target
MGC; SCARJ; AGER; RAGE; SCARJ1; Advanced glycosylation end product-specific receptor; advanced glycosylation end-product specific receptor; MGC2235; Receptor for Advanced Glycation End products; Receptor for advanced glycosylation end products
Clonality
Monoclonal,Recombinant
Clone
2B13
Conjugation
Unconjugated
Applications
WB
Field of Research
Neuroscience; Cardiovascular
Purification
Protein A
Concentration
0.2 mg/mL
Dilution
WB 1:2000-1:10000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
43 kDa
Observed Molecular Weight
52,58 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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