Recombinant Claudin 3 Monoclonal Antibody
Product Specifications
Background
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is also a low-affinity receptor for Clostridium perfringens enterotoxin, and shares aa sequence similarity with a putative apoptosis-related protein found in rat.
Abbreviation
Claudin 3
UniProt
O15551
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant Human Claudin 3 protein
Target
RVP; CLDN; HRVP; CPE-receptor; C7orf1 CPETR; C7orf; CPETR; CLDN3; C7orf1; CPE-R2; CPETR2; HRVP1; RVP1; claudin-3; CPE-R 2; CPE-receptor 2; C7orf1 CPETR2; Claudin 3; Claudin3; CLD3; CLDN 3; Clostridium perfringens enterotoxin receptor 2; CPE R2; CPE receptor 2; CPETR 2; HRVP 1; Rat ventral prostate 1 like protein; Rat ventral prostate.1 protein homolog; Ventral prostate.1 like protein; Ventral prostate.1 protein homolog
Clonality
Monoclonal,Recombinant
Clone
2B10
Conjugation
Unconjugated
Applications
WB
Field of Research
Signal Transduction; Cancer; Metabolism
Purification
Protein A
Concentration
0.2 mg/mL
Dilution
WB 1:2000-1:10000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
23 kDa
Observed Molecular Weight
20 kDa
Isotype
IgG, κ
Available Sizes
Frequently Asked Questions
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