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Recombinant Claudin 3 Monoclonal Antibody

Product Specifications

Background

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is also a low-affinity receptor for Clostridium perfringens enterotoxin, and shares aa sequence similarity with a putative apoptosis-related protein found in rat.

Abbreviation

Claudin 3

UniProt

O15551

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Recombinant Human Claudin 3 protein

Target

RVP; CLDN; HRVP; CPE-receptor; C7orf1 CPETR; C7orf; CPETR; CLDN3; C7orf1; CPE-R2; CPETR2; HRVP1; RVP1; claudin-3; CPE-R 2; CPE-receptor 2; C7orf1 CPETR2; Claudin 3; Claudin3; CLD3; CLDN 3; Clostridium perfringens enterotoxin receptor 2; CPE R2; CPE receptor 2; CPETR 2; HRVP 1; Rat ventral prostate 1 like protein; Rat ventral prostate.1 protein homolog; Ventral prostate.1 like protein; Ventral prostate.1 protein homolog

Clonality

Monoclonal,Recombinant

Clone

2B10

Conjugation

Unconjugated

Applications

WB

Field of Research

Signal Transduction; Cancer; Metabolism

Purification

Protein A

Concentration

0.2 mg/mL

Dilution

WB 1:2000-1:10000

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

23 kDa

Observed Molecular Weight

20 kDa

Isotype

IgG, κ

Available Sizes

Frequently Asked Questions

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