Recombinant Fascin Monoclonal Antibody
Product Specifications
Background
This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15.
Abbreviation
Fascin
UniProt
Q16658
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant Human Fascin protein
Target
Fan; FSCN; FSCN1; FAN1; HSN; SNL; p55; fascin;55 kDa actin-bundling protein; FSCN1; FAN1; HSN; SNL; p55; fascin; Singed-like protein
Clonality
Monoclonal,Recombinant
Clone
1A8
Conjugation
Unconjugated
Applications
WB
Field of Research
Signal Transduction
Purification
Protein A
Concentration
0.2 mg/mL
Dilution
WB 1:10000-1:20000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Product MSDS
https://789.bio/eb/EfLbrv0X
Calculated Molecular Weight
54 kDa
Observed Molecular Weight
54 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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