Recombinant FCGRT & B2M Heterodimer Monoclonal Antibody
Product Specifications
Background
FCGRT & B2M heterodimer protein (FcRn complex) consist of two subunits: p51 (equivalent to FCGRT), and p14 (equivalent to beta-2-microglobulin), and forms an MHC class I-like heterodimer. Fc fragment of IgG, receptor, transporter, alpha (FCGRT) binds to the Fc region of monomeric immunoglobulins gamma and mediates the uptake of IgG from milk. FCGRT possible role in transfer of immunoglobulin G from mother to fetus. Beta-2-microglobulin (B2M) is a component of the class I major histocompatibility complex (MHC) and involved in the presentation of peptide antigens to the immune system.
Abbreviation
FCGRT & B2M
UniProt
P55899&P61769
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant Human FCGRT & B2M Heterodimer protein
Target
FCGRT; FCRN; alpha-chain; alpha; heavy chain; intestinal; receptor transporter; Alpha chain; Fc fragment of IgG; FCGRN_HUMAN; FcRn alpha chain; IgG Fc fragment receptor transporter alpha chain; IgG Gc receptor; IgG receptor FcRn large subunit p51; IgG receptor FcRn large subunit p51 precursor; Immunoglobulin receptor; Neonatal Fc receptor; IMD; Beta-2-microglobulin form pI; CDABP; B2M; IMD43; B2MG; Beta 2 microglobin; Beta 2 microglobulin; Beta 2 microglobulin precursor; Beta chain of mhc class 1 proteins; Beta chain of MHC class I molecules; Beta-2-Microglobulin; Beta-2-microglobulin form pI 5.3; β2M; β2-Microglobulin; CDABP0092; HDCMA22P
Clonality
Monoclonal
Clone
12B11
Conjugation
Unconjugated
Applications
IHC-P
Field of Research
Immunology; Cardiovascular; Cancer
Purification
Protein A
Concentration
1 mg/mL
Dilution
IHC-P 1:100-1:500
Buffer
0.2 μm filtered solution in PBS
Shipping Conditions
Ice bag
Storage Conditions
This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Isotype
IgG
Curated Selection
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