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Recombinant Hemopexin/HPX Monoclonal Antibody

Product Specifications

Background

Hemopexin (HPX) is the plasma protein responsible for scavenging heme, thus preventing heme-mediated oxidative stress and heme-bound iron loss. In addition, hemopexin blocks heme activation of immune receptors and vascular inflammatory processes. It is mainly expressed in liver, the synthesis of which is induced after inflammation. Alterations of plasma hemopexin level have been linked to disorders like atherosclerosis and inflammatory diseases.

Abbreviation

HPX

UniProt

P20059

Host

Rabbit

Reactivity

Rat

Immunogen

Recombinant Rat Hemopexin/HPX Protein

Target

Hpx; HEMO; Beta-1B-glycoprotein; hemopexin

Clonality

Monoclonal

Clone

12B10

Conjugation

Unconjugated

Applications

WB; IP

Purification

Protein A

Concentration

1 mg/mL

Dilution

WB 1:500-1:2000; IP 5-10 μL/mg of lysate

Buffer

0.2 μm filtered solution in PBS

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

52 kDa

Observed Molecular Weight

70 kDa

Isotype

IgG

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