Recombinant Hemopexin/HPX Monoclonal Antibody
Product Specifications
Background
Hemopexin (HPX) is the plasma protein responsible for scavenging heme, thus preventing heme-mediated oxidative stress and heme-bound iron loss. In addition, hemopexin blocks heme activation of immune receptors and vascular inflammatory processes. It is mainly expressed in liver, the synthesis of which is induced after inflammation. Alterations of plasma hemopexin level have been linked to disorders like atherosclerosis and inflammatory diseases.
Abbreviation
HPX
UniProt
P20059
Host
Rabbit
Reactivity
Rat
Immunogen
Recombinant Rat Hemopexin/HPX Protein
Target
Hpx; HEMO; Beta-1B-glycoprotein; hemopexin
Clonality
Monoclonal
Clone
12B10
Conjugation
Unconjugated
Applications
WB; IP
Purification
Protein A
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000; IP 5-10 μL/mg of lysate
Buffer
0.2 μm filtered solution in PBS
Shipping Conditions
Ice bag
Storage Conditions
This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
52 kDa
Observed Molecular Weight
70 kDa
Isotype
IgG
Curated Selection
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