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Recombinant CD38 Monoclonal Antibody

Product Specifications

Background

The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Cluster of differentiation 38 (CD38), also known as ADP-ribosyl cyclase, is a glycoprotein found on the surface of many immune cells (white blood cells), including CD4+, CD8+, B and natural killer cells. It shares several characteristics with ADP-ribosyl cyclase 2 CD157. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD+ to ADP-ribose. It also functions in cell adhesion, signal transduction and calcium signaling. CD38 has been used as a prognostic marker in leukemia. It can also be used to identify plasma cells.

Abbreviation

CD38

UniProt

P56528

Host

Rabbit

Reactivity

Mouse

Immunogen

Recombinant Mouse CD38 protein

Target

ADPRC 1-rs; cADPr hydrolase; Acute lymphoblastic leukemia cells antigen CD; Cd38-rs;2'-phospho-cyclic-ADP-ribose transferase; Acute lymphoblastic leukemia cells antigen CD38; ADP ribosyl cyclase; ADPRC 1; ADPRC 1-rs1; ADPRC1; ADP-ribosyl cyclase 1; cADPr hydrolase 1; CD38 antigen; CD38 antigen (p45) ; CD38 molecule; CD38H; Cd38-rs1; Cyclic ADP ribose hydrolase; Cyclic ADP-ribose Hydrolase; Cyclic ADP-ribose hydrolase 1; EC 3.2.2.5; I-19; NAD (+) nucleosidase; NIMR5 antigen; NIM-R5 antigen; p45; T10; Cd38; ADP-ribosyl cyclase; ADP ribosyl cyclase; ADPRC1; CD38 antigen; CD38 molecule; CD38H; Cyclic ADP ribose hydrolase; EC 3.2.2.5; I-19; NIMR5 antigen; p45; T10; Cyclic ADP-ribose Hydrolase

Clonality

Monoclonal

Clone

7C5

Conjugation

Unconjugated

Applications

IHC-P

Purification

Protein A

Concentration

1 mg/mL

Dilution

IHC-P 1:250-1:1000

Buffer

0.2 μm filtered solution in PBS

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Product MSDS

https://789.bio/eb/yIgA0g4V

Isotype

IgG

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