Recombinant 4-1BBL/CD137L/TNFSF9 Monoclonal Antibody

4-1BB ligand is the high affinity ligand of 4-1BB, also known as CD137L or TNFSF9. It is shown to be a type II surface glycoprotein belonging to the TNF superfamily. Expression of 4-1BBL is restricted to APCs, such as dendritic cells, macrophages, and activated B cells. Members of the TNF-TNF receptor superfamily have been shown to play critical roles in regulating cellular activation, differentiation and apoptosis. Several studies have reported that 4-1BBL/4-1BB interaction provided a co-stimulatory signal to T cells, and increased T cell proliferation and cytokines production. In addition, 4-1BBL is involved in cancers, infectious diseases and autoimmune diseases.

Tumor necrosis factor ligand superfamily member; D8Ertd;4-1BB ligand;4-1BBL; BAF; BL; BLyS; D8Ertd387; D8Ertd387e; member 13b; TAL; TALL1; TALL-1; THANK; Tnfsf13b; TNFSF20; Tnlg7a; tumor necrosis factor (ligand) superfamily; Tumor necrosis factor ligand superfamily member 9; zTNF; zTNF4; Cd137l; Cd157l; Ly63l; Tnfsf9; Ly63l; Tnfsf13b

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.