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Recombinant CD16-2/FCGR4 Monoclonal Antibody

Product Specifications

Background

FcgRIV, also known as CD16-2, is an intermediate-affinity activating receptor for IgG2a and IgG2b. CD16-2 is the mouse homolog of human FcgRIIIA. CD16-2 is a low-affinity IgE receptor for all allotypes and the ligation of FcgRIV by antigen-IgE immune complexes promotes macrophage-mediated phagocytosis and is involved in lung inflammation.

Abbreviation

FCGR4

UniProt

A0A0B4J1G0

Host

Rabbit

Reactivity

Mouse

Immunogen

Recombinant Mouse FCGR4 protein

Target

Fcgr; Fcgr4;4833442P21Rik;4833442P21Rik Protein; CD16-2; CD16-2 Protein; FcgammaRIV; FcgammaRIV Protein; Fcgr3a; Fcgr3a Protein; FcgRIV; FcgRIV Protein; Fcrl3; Fcrl3 Protein; Low Affinity Immunoglobulin Gamma Fc Region Receptor IV; Mouse

Clonality

Monoclonal

Clone

8B6

Conjugation

Unconjugated

Applications

FCM; ICC/IF

Purification

Protein A

Concentration

1 mg/mL

Dilution

ICC/IF 1:50-1:1000; FCM 1:25-1:100

Buffer

0.2 μm filtered solution in PBS

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Isotype

IgG

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