Recombinant Cathepsin D/CTSD Monoclonal Antibody
Product Specifications
Background
This gene encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. This enzyme exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease.
Abbreviation
CTSD
UniProt
P07339
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant Human Cathepsin D/CTSD protein
Target
CLN; CLN10; CPSD; HEL-S-130P; Cathepsin D; CTSD
Clonality
Monoclonal
Clone
3G8
Conjugation
Unconjugated
Applications
WB; IHC-P
Field of Research
Neuroscience; Signal Transduction; Cancer; Cell Biology
Purification
Protein A
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000; IHC-P 1:100-1:500
Buffer
0.2 μm filtered solution in PBS
Shipping Conditions
Ice bag
Storage Conditions
This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Product MSDS
https://789.bio/eb/fOIcEF0d
Calculated Molecular Weight
45 kDa
Observed Molecular Weight
31 kDa
Isotype
IgG
Curated Selection
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