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Recombinant Cathepsin D/CTSD Monoclonal Antibody

Product Specifications

Background

This gene encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. This enzyme exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease.

Abbreviation

CTSD

UniProt

P07339

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant Human Cathepsin D/CTSD protein

Target

CLN; CLN10; CPSD; HEL-S-130P; Cathepsin D; CTSD

Clonality

Monoclonal

Clone

3G8

Conjugation

Unconjugated

Applications

WB; IHC-P

Field of Research

Neuroscience; Signal Transduction; Cancer; Cell Biology

Purification

Protein A

Concentration

1 mg/mL

Dilution

WB 1:500-1:2000; IHC-P 1:100-1:500

Buffer

0.2 μm filtered solution in PBS

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

45 kDa

Observed Molecular Weight

31 kDa

Isotype

IgG

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